Anti-Ephrin-B2 antibody produced in goat, affinity isolated antibody

Biochem/physiol Actions

Ephrin B2 binds to EPH receptor B, a protein-tyrosine kinase family that belongs to the ephrin receptor subfamily. EphB receptors and EphrinB ligands have a regulatory effect on endothelial cell function, angiogenesis, migration, cell growth and survival.

Disclaimer

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General description

By immunoblotting and ELISA, the antibody shows ~50% cross-reactivity with recombinant human ephrin-B5 and 15% cross-reactivity with mouse ephrin-B1.

Immunogen

recombinant mouse ephrin-B2, expressed in NSO cells.

Physical form

Lyophilized from a 0.2 µm filtered solution in phosphate buffered saline, pH 7.4 with 5% trehalose.